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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   SMCR7L Antibody (N-term)   

SMCR7L Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SMCR7L Antibody (N-term) AP5571a
    SMCR7L Antibody (N-term) (Cat. #AP5571a) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the SMCR7L antibody detected SMCR7L protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQG6
Other Accession NP_061881.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51293 Da
Antigen Region 105-132 aa
Additional Information
Gene ID 54471
Other Names Mitochondrial dynamics protein MID51, Mitochondrial dynamics protein of 51 kDa, Mitochondrial elongation factor 1, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like, SMCR7-like protein, MIEF1, MID51, SMCR7L
Target/Specificity This SMCR7L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-132 amino acids from the N-terminal region of human SMCR7L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSMCR7L Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MIEF1
Synonyms MID51, SMCR7L
Function Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.
Cellular Location Mitochondrion outer membrane; Single-pass membrane protein
Tissue Location Expression is relatively high in heart, skeletal muscle, pancreas and kidney
Research Areas
Citations (0)

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SMCR7L belongs to the SMCR7 family. The specific function of this protein remains unknown.


Jin, J., et al. Curr. Biol. 14(16):1436-1450(2004)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
Dunham, I., et al. Nature 402(6761):489-495(1999)

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$ 295.00
$ 99.00
Cat# AP5571a
(40 western blots)
Availability: In Stock
Bulk Size
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