|Application ||WB, IHC-P, FC, E|
|Calculated MW||27590 Da|
|Antigen Region||181-210 aa|
|Other Names||Fibroblast growth factor-binding protein 3, FGF-BP3, FGF-binding protein 3, FGFBP-3, FGFBP3, C10orf13|
|Target/Specificity||This FGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the C-terminal region of human FGFBP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FGFBP3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.|
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Provided below are standard protocols that you may find useful for product applications.
Zhang, W., et al. J. Biol. Chem. 283(42):28329-28337(2008)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
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