|Application ||WB, IHC-P, FC, E|
|Calculated MW||147163 Da|
|Antigen Region||388-417 aa|
|Other Names||Regulator of G-protein signaling 22, RGS22, RGS22|
|Target/Specificity||This RGS22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 388-417 amino acids from the Central region of human RGS22.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RGS22 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.|
|Cellular Location||Cytoplasm. Nucleus. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus|
|Tissue Location||Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
RGS22 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (By similarity).
Hu, Y., et al. Biol. Reprod. 79(6):1021-1029(2008)
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