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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RGS22 Antibody (Center)   

RGS22 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RGS22 Antibody (Center) AP5631c
    RGS22 Antibody (Center) (Cat. #AP5631c) western blot analysis in Hela cell line lysates (15ug/lane).This demonstrates the RGS22 antibody detected the RGS22 protein (arrow).
  • WB - RGS22 Antibody (Center) AP5631c
    RGS22 Antibody (Center) (Cat. #AP5631c) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the RGS22 antibody detected the RGS22 protein (arrow).
  • IHC-P - RGS22 Antibody (Center) AP5631c
    RGS22 Antibody (Center) (Cat. #AP5631c) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RGS22 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - RGS22 Antibody (Center) AP5631c
    RGS22 Antibody (Center) (Cat. #AP5631c) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NE09
Other Accession NP_056483.3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 147163 Da
Antigen Region 388-417 aa
Additional Information
Gene ID 26166
Other Names Regulator of G-protein signaling 22, RGS22, RGS22
Target/Specificity This RGS22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 388-417 amino acids from the Central region of human RGS22.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRGS22 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGS22
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
Cellular Location Cytoplasm. Nucleus. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus
Tissue Location Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level).
Research Areas
Citations (0)

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RGS22 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (By similarity).


Hu, Y., et al. Biol. Reprod. 79(6):1021-1029(2008)

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Cat# AP5631c
(40 western blots)
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