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LDHD Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, IHC-P, E |
|---|---|
| Primary Accession | Q86WU2 |
| Other Accession | NP_705690.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 54871 Da |
| Antigen Region | 35-62 aa |
| Gene ID | 197257 |
|---|---|
| Other Names | Probable D-lactate dehydrogenase, mitochondrial, DLD, Lactate dehydrogenase D, LDHD (HGNC:19708) |
| Target/Specificity | This LDHD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human LDHD. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LDHD Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LDHD (HGNC:19708) |
|---|---|
| Function | Involved in D-lactate, but not L-lactate catabolic process. |
| Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:Q7TNG8}. |
| Tissue Location | Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
LDHD belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq].
References
Dastani, Z., et al. Eur. J. Hum. Genet. (2009) In press :
Flick, M.J., et al. Biochem. Biophys. Res. Commun. 295(4):910-916(2002)
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