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FOXC2 Antibody (Center S174)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FOXC2 Antibody (Center S174) AP5750c
    FOXC2 Antibody (Center S174) (Cat. #AP5750c) western blot analysis in A2058 cell line lysates (15ug/lane).This demonstrates the FOXC2 antibody detected the FOXC2 protein (arrow).
  • IHC-P - FOXC2 Antibody (Center S174) AP5750c
    FOXC2 Antibody (Center S174) (Cat. #AP5750c) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FOXC2 Antibody (Center S174) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - FOXC2 Antibody (Center S174) AP5750c
    FOXC2 Antibody (Center S174) (Cat. #AP5750c) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99958
Other Accession NP_005242
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53719 Da
Antigen Region 159-186 aa
Additional Information
Gene ID 2303
Other Names Forkhead box protein C2, Forkhead-related protein FKHL14, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14, FOXC2, FKHL14, MFH1
Target/Specificity This FOXC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-186 amino acids from the Central region of human FOXC2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFOXC2 Antibody (Center S174) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXC2
Synonyms FKHL14, MFH1
Function Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089, ECO:0000269|PubMed:23878394}
Research Areas
Citations (0)

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FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.


van Dongen, M.J., et al. J. Mol. Biol. 296(2):351-359(2000)
Mangion, J., et al. Am. J. Hum. Genet. 65(2):427-432(1999)
Miura, N., et al. Genomics 41(3):489-492(1997)
Kaestner, K.H., et al. Development 122(6):1751-1758(1996)

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Cat# AP5750c
(40 western blots)
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