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GM2A Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GM2A Antibody (N-term) AP5841a
    GM2A Antibody (N-term) (Cat. #AP5841a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the GM2A antibody detected the GM2A protein (arrow).
  • WB - GM2A Antibody (N-term) AP5841a
    GM2A Antibody (N-term) (Cat. #AP5841a) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the GM2A antibody detected the GM2A protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17900
Other Accession Q8HXX6, NP_000396.2
Reactivity Human, Mouse
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20838 Da
Antigen Region 25-54 aa
Additional Information
Gene ID 2760
Other Names Ganglioside GM2 activator, Cerebroside sulfate activator protein, GM2-AP, Sphingolipid activator protein 3, SAP-3, Ganglioside GM2 activator isoform short, GM2A
Target/Specificity This GM2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human GM2A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGM2A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GM2A
Function The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta- hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
Cellular Location Lysosome.
Research Areas
Citations ( 0 )
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$ 295.00
$ 99.00
Cat# AP5841a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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