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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, FC, E |
|---|---|
| Primary Accession | P49069 |
| Other Accession | NP_001736.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Antigen Region | 111-138 aa |
| Other Names | Calcium signal-modulating cyclophilin ligand, CAML, CAMLG, CAML |
|---|---|
| Target/Specificity | This CAMLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human CAMLG. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CAMLG Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CAMLG |
|---|---|
| Synonyms | CAML |
| Function | Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Ubiquitous. Highest levels in brain, testis and ovary EMBL; U18242; AAA59420.1; -; mRNA EMBL; AK313156; BAG35974.1; -; mRNA EMBL; CH471062; EAW62243.1; -; Genomic_DNA EMBL; CH471062; EAW62244.1; -; Genomic_DNA EMBL; BC130325; AAI30326.1; -; mRNA EMBL; AF068179; AAC23596.1; -; mRNA CCDS; CCDS4178.1; - PIR; S47594; S47594 RefSeq; NP_001736.1; NM_001745.3 UniGene; Hs.529846; - ProteinModelPortal; P49069; - BioGrid; 107269; 17 CORUM; P49069; - IntAct; P49069; 32 STRING; 9606.ENSP00000297156; - DrugBank; DB00091; Cyclosporine TCDB; 3.A.19.1.1; the tms recognition/insertion complex (trc) family iPTMnet; P49069; - PhosphoSitePlus; P49069; - BioMuta; CAMLG; - DMDM; 1345662; - EPD; P49069; - MaxQB; P49069; - PaxDb; P49069; - PeptideAtlas; P49069; - PRIDE; P49069; - ProteomicsDB; 55961; - DNASU; 819; - Ensembl; ENST00000297156; ENSP00000297156; ENSG00000164615 GeneID; 819; - KEGG; hsa:819; - UCSC; uc003kzt.4; human CTD; 819; - DisGeNET; 819; - EuPathDB; HostDB:ENSG00000164615.4; - GeneCards; CAMLG; - H-InvDB; HIX0164331; - HGNC; HGNC:1471; CAMLG HPA; HPA052636; - HPA; HPA056472; - MIM; 601118; gene neXtProt; NX_P49069; - OpenTargets; ENSG00000164615; - PharmGKB; PA26053; - eggNOG; ENOG410IEK3; Eukaryota eggNOG; ENOG4111HUY; LUCA GeneTree; ENSGT00390000015996; - HOGENOM; HOG000220891; - HOVERGEN; HBG050786; - InParanoid; P49069; - KO; K22385; - OMA; HHGLEQY; - OrthoDB; EOG091G0HL4; - PhylomeDB; P49069; - TreeFam; TF331902; - ChiTaRS; CAMLG; human GeneWiki; CAMLG; - GenomeRNAi; 819; - PMAP-CutDB; P49069; - PRO; PR:P49069; - Proteomes; UP000005640; Chromosome 5 Bgee; ENSG00000164615; - CleanEx; HS_CAMLG; - ExpressionAtlas; P49069; baseline and differential Genevisible; P49069; HS GO; GO:0005783; C:endoplasmic reticulum; IDA:MGI GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0016020; C:membrane; HDA:UniProtKB GO; GO:0006952; P:defense response; TAS:ProtInc GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Ensembl GO; GO:0001881; P:receptor recycling; IEA:Ensembl GO; GO:0007165; P:signal transduction; TAS:ProtInc GO; GO:0016032; P:viral process; IEA:UniProtKB-KW InterPro; IPR016719; Ca_signal-mod_cyclophilin_lig PANTHER; PTHR15026; PTHR15026; 1 Pfam; PF14963; CAML; 1 PIRSF; PIRSF018259; CAML; 1 1: Evidence at protein level; Complete proteome; Host-virus interaction; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix CHAIN 1 296 Calcium signal-modulating cyclophilin ligand /FTId=PRO_0000089291 TOPO_DOM 1 189 Cytoplasmic. TRANSMEM 190 210 Helical. TOPO_DOM 211 240 Extracellular. TRANSMEM 241 257 Helical. TOPO_DOM 258 296 Cytoplasmic. MOD_RES 55 55 Phosphoserine VARIANT 78 78 V -> I (in dbSNP:rs12657663) /FTId=VAR_024297 VARIANT 100 100 G -> S (in dbSNP:rs11552197) /FTId=VAR_050710 SEQUENCE 296 AA; 32953 MW; 22DCD8CF022FEF09 CRC64; MESMAVATDG GERPGVPAGS GLSASQRRAE LRRRKLLMNS EQRINRIMGF HRPGSGAEEE SQTKSKQQDS DKLNSLSVPS VSKRVVLGDS VSTGTTDQQG GVAEVKGTQL GDKLDSFIKP PECSSDVNLE LRQRNRGDLT ADSVQRGSRH GLEQYLSRFE EAMKLRKQLI SEKPSQEDGN TTEEFDSFRI FRLVGCALLA LGVRAFVCKY LSIFAPFLTL QLAYMGLYKY FPKSEKKIKT TVLTAALLLS GIPAEVINRS MDTYSKMGEV FTDLCVYFFT FIFCHELLDY WGSEVP |
Research Areas
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Cat# AP5885c
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