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TRAM2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q15035 |
| Other Accession | NP_036420.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 43328 Da |
| Antigen Region | 342-370 aa |
| Gene ID | 9697 |
|---|---|
| Other Names | Translocating chain-associated membrane protein 2, TRAM2, KIAA0057 |
| Target/Specificity | This TRAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-370 amino acids from the C-terminal region of human TRAM2. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TRAM2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRAM2 |
|---|---|
| Synonyms | KIAA0057 |
| Function | Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) (PubMed:27499293). |
| Cellular Location | Membrane; Multi-pass membrane protein |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 365.00
$ 140.00
Cat# AP5996b
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