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EDG6 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - EDG6 Antibody (N-term) AP6142a
    EDG6 Antibody (R23) (Cat. #AP6142a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the EDG6 antibody detected the EDG6 protein (arrow).
  • WB - EDG6 Antibody (N-term) AP6142a
    EDG6 Antibody (R23) (Cat. #AP6142a) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the EDG6 antibody detected the EDG6 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95977
Other Accession NP_003766
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41623 Da
Antigen Region 8-37 aa
Additional Information
Gene ID 8698
Other Names Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6, S1PR4, EDG6
Target/Specificity This EDG6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human EDG6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEDG6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name S1PR4
Synonyms EDG6
Function Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung
Research Areas
Citations ( 0 )


EDG6 is a member of the G protein-coupled receptors, as well as the EDG family of proteins. It participates in endothelial differentiation, and may regulate lymphocyte cell signaling. It is a member of the lysophospholipid/lysosphingolipid receptor family.


Contos, J.J., et al., FEBS Lett. 531(1):99-102 (2002).
Yamazaki, Y., et al., Biochem. Biophys. Res. Commun. 268(2):583-589 (2000).
Graler, M.H., et al., Genomics 53(2):164-169 (1998).

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$ 295.00
$ 99.00
Cat# AP6142a
(40 western blots)
Availability: In Stock
Bulk Size
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