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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Leptin (LEP) Antibody (C-term)   

Leptin (LEP) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Leptin (LEP) Antibody (C-term) AP6150a
    Western blot analysis of hLep-R149 (Cat. #AP6150a) in MDA-MB231 cell line lysates (35ug/lane). LEP (arrow) was detected using the purified Pab.
  • IF - Leptin (LEP) Antibody (C-term) AP6150a
    Confocal immunofluorescent analysis of Leptin (LEP) Antibody (C-term)(Cat#AP6150a) with HepG2 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P41159
Other Accession NP_000221
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 18641 Da
Antigen Region 134-166 aa
Additional Information
Gene ID 3952
Other Names Leptin, Obese protein, Obesity factor, LEP, OB, OBS
Target/Specificity This Leptin (LEP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the C-terminal region of human Leptin (LEP).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLeptin (LEP) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LEP
Synonyms OB, OBS
Function May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
Cellular Location Secreted.
Research Areas
Citations (0)

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Leptin (LEP) is an adipocyte-secreted protein that regulates body fat and endocrine functions. Leptin is similar to the mouse obesity protein encoded by the obese gene (ob). In mouse studies, mutations in this gene are linked to severe and morbid obesity.


Tank, J., et al., J. Clin. Endocrinol. Metab. 88(10):4955-4959 (2003).
Silha, J.V., et al., Eur. J. Endocrinol. 149(4):331-335 (2003).
Kazumi, T., et al., Metab. Clin. Exp. 52(9):1113-1116 (2003).
Mullington, J.M., et al., J. Neuroendocrinol. 15(9):851-854 (2003).
Catalano, S., et al., J. Biol. Chem. 278(31):28668-28676 (2003).

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$ 295.00
$ 99.00
Cat# AP6150a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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