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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   MMP10 Antibody (C-term)   

MMP10 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MMP10 Antibody (C-term) AP6194a
    Western blot analysis of hMMP10-R409 (Cat. #AP6194a) in mouse spleen tissue lysates (35ug/lane). MMP10 (arrow) was detected using the purified Pab.
  • IHC-P - MMP10 Antibody (C-term) AP6194a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09238
Other Accession NP_002416
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54151 Da
Antigen Region 394-423 aa
Additional Information
Gene ID 4319
Other Names Stromelysin-2, SL-2, Matrix metalloproteinase-10, MMP-10, Transin-2, MMP10, STMY2
Target/Specificity This MMP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human MMP10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMMP10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP10
Synonyms STMY2
Function Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
Citations (0)

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP10 degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.


Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).
Pendas, A.M., et al., Genomics 37(2):266-268 (1996).
Jung, J.Y., et al., Ann. Genet. 33(1):21-23 (1990).
Sirum, K.L., et al., Biochemistry 28(22):8691-8698 (1989).
Muller, D., et al., Biochem. J. 253(1):187-192 (1988).

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Cat# AP6194a
(40 western blots)
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