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HSC70 Interacting Protein HIP (ST13) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - HSC70 Interacting Protein HIP (ST13) Antibody AP6247a
    Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with ST13 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • WB - HSC70 Interacting Protein HIP (ST13) Antibody AP6247a
    Western blot analysis of anti-ST13 Antibody (N-term) (Cat.#AP6247a) pre-incubated with and without blocking peptide (BP6247a) in A2058 cell line lysate. ST13(arrow) was detected using the purified Pab .
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50502
Other Accession Q8IZP2, NP_003923
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41332 Da
Antigen Region 50-80 aa
Additional Information
Gene ID 6767
Other Names Hsc70-interacting protein, Hip, Aging-associated protein 2, Progesterone receptor-associated p48 protein, Protein FAM10A1, Putative tumor suppressor ST13, Renal carcinoma antigen NY-REN-33, Suppression of tumorigenicity 13 protein, ST13, AAG2, FAM10A1, HIP, SNC6
Target/Specificity This HSC70 Interacting Protein HIP (ST13) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from human HSC70 Interacting Protein HIP (ST13).
Dilution IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHSC70 Interacting Protein HIP (ST13) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ST13
Synonyms AAG2, FAM10A1, HIP, SNC6
Function One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity).
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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ST13 is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this protein is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor.


Rajapandi, T., et al., J. Biol. Chem. 275(29):22597-22604 (2000).
Morishima, Y., et al., J. Biol. Chem. 275(10):6894-6900 (2000).
Chen, S., et al., J. Biol. Chem. 273(52):35194-35200 (1998).
Johnson, B.D., et al., J. Biol. Chem. 273(6):3679-3686 (1998).
Cao, J., et al., J. Cancer Res. Clin. Oncol. 123(8):447-451 (1997).

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$ 295.00
$ 99.00
Cat# AP6247a
(40 western blots)
Availability: In Stock
Bulk Size
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