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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   VEGFD (VEGF4) Antibody (C-term)   

VEGFD (VEGF4) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - VEGFD (VEGF4) Antibody (C-term) AP6292B
    Western blot analysis of anti-VEGF4 Antibody (C-term) Pab (AP6292b) in 293 cell line lysates. VEGF4 Antibody (C-term)(arrow) was detected using the purified Pab.
  • IHC-P - VEGFD (VEGF4) Antibody (C-term) AP6292B
    VEGFD (VEGF4) Antibody (C-term) (Cat. #AP6292B)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VEGFD (VEGF4) Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43915
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40444 Da
Antigen Region 322-352 aa
Additional Information
Gene ID 2277
Other Names Vascular endothelial growth factor D, VEGF-D, c-Fos-induced growth factor, FIGF, FIGF, VEGFD
Target/Specificity This VEGFD (VEGF4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human VEGFD (VEGF4).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsVEGFD (VEGF4) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms VEGFD
Function Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
Cellular Location Secreted.
Tissue Location Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.


Orlandini, M., et al., J. Biol. Chem. 278(45):44650-44656 (2003).
McColl, B.K., et al., J. Exp. Med. 198(6):863-868 (2003).
Rissanen, T.T., et al., Circ. Res. 92(10):1098-1106 (2003).
Nakamura, Y., et al., Clin. Cancer Res. 9(2):716-721 (2003).
Yokoyama, Y., et al., Br. J. Cancer 88(2):237-244 (2003).

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Cat# AP6292B
(40 western blots)
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