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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Claudin 2 (CLDN2) Antibody (N-term)   

Claudin 2 (CLDN2) Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Claudin 2 (CLDN2) Antibody (N-term) AP6309a
    Western blot analysis of anti-CLDN2 Antibody (N-term) (Cat. #AP6309a) in mouse heart tissue lysates (35ug/lane). CLDN2(arrow) was detected using the purified Pab.
  • IHC-P - Claudin 2 (CLDN2) Antibody (N-term) AP6309a
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CLDN2 (Human N-term) (Cat.#AP6309a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P57739
Other Accession O88552, Q765P1, NP_065117
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24549 Da
Antigen Region 135-164 aa
Additional Information
Gene ID 9075
Other Names Claudin-2, SP82, CLDN2
Target/Specificity This Claudin 2 (CLDN2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human Claudin 2 (CLDN2).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsClaudin 2 (CLDN2) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLDN2
Function Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.
Cellular Location Cell junction, tight junction. Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.


Morita,K., Proc. Natl. Acad. Sci. U.S.A. 96 (2), 511-516 (1999)
Furuse,M., J. Cell Biol. 141 (7), 1539-1550 (1998)

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Cat# AP6309a
(40 western blots)
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