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Kallikrein 3 Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP6322b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
  • Specification
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  • Reviews
  • Protocols
  • Backgrounds

Kallikrein 3 Antibody (C-term) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionP07288
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW28741 Da

Kallikrein 3 Antibody (C-term) - Additional info

Gene ID 354
Other Names
KLK3; APS; Prostate-specific antigen; Gamma-seminoprotein; Kallikrein-3; P-30 antigen; Semenogelase
Target/Specificity
This Kallikrein 3 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227~257 amino acids from the C-terminal region of human KLK3.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
Kallikrein 3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

Kallikrein 3 Antibody (C-term) - Protein Information

Name KLK3
Synonyms APS
Function
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum
Cellular Location
Secreted.

Kallikrein 3 Antibody (C-term) - Related products

AP6322b: Kallikrein 3 Antibody (C-term)

RI12929: KLK3 predesign siRNA

DC01716: Human KLK3 cDNA Clone

LY11024a: KLK3 Over-expression Lysate

BP6322b: KLK3 Antibody (C-term) Blocking Peptide

AO1141a: PSA (KLK3) Antibody

AJ1659a: Prostate-Specific Antigen (PSA) Antibody

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma.

REFERENCES

Binnie, M.C., et al., Prostate 63(4):309-315 (2005). Habib, F.K., et al., Int. J. Cancer 114(2):190-194 (2005). Laidler, P., et al., Arch. Biochem. Biophys. 435(1):1-14 (2005). Dallas, S.L., et al., J. Cell. Physiol. 202(2):361-370 (2005). Olsson, A.Y., et al., Genomics 84(1):147-156 (2004).