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Kallikrein 3 Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP6322b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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Kallikrein 3 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | P07288 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 28741 Da |
Kallikrein 3 Antibody (C-term) - Additional info | |
| Gene ID 354 | |
| Other Names KLK3; APS; Prostate-specific antigen; Gamma-seminoprotein; Kallikrein-3; P-30 antigen; Semenogelase | |
| Target/Specificity This Kallikrein 3 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227~257 amino acids from the C-terminal region of human KLK3. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Kallikrein 3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Kallikrein 3 Antibody (C-term) - Protein Information | |
| Name KLK3 | |
| Synonyms APS | |
| Function Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum | |
| Cellular Location Secreted. | |
Kallikrein 3 Antibody (C-term) - Related products
AP6322b: Kallikrein 3 Antibody (C-term)
DC01716: Human KLK3 cDNA Clone
LY11024a: KLK3 Over-expression Lysate
Kallikrein 3 Antibody (C-term) - Application data
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Western blot analysis of anti-KLK3 Pab (Cat. #AP6322b) in mouse brain tissue lysate.KLK3(arrow) was detected using the purified Pab.
Kallikrein 3 Antibody (C-term) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma.
REFERENCES
Binnie, M.C., et al., Prostate 63(4):309-315 (2005). Habib, F.K., et al., Int. J. Cancer 114(2):190-194 (2005). Laidler, P., et al., Arch. Biochem. Biophys. 435(1):1-14 (2005). Dallas, S.L., et al., J. Cell. Physiol. 202(2):361-370 (2005). Olsson, A.Y., et al., Genomics 84(1):147-156 (2004).