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EDNRA Antibody (Center)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6507c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP6507c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
EDNRA Antibody (Center) - Product info | |
| Application | WB, IF, FC
|
| Primary Accession | P25101 |
| Other Accession | P26684, Q61614 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 48722 Da |
EDNRA Antibody (Center) - Additional info | |
| Gene ID 1909 | |
| Other Names EDNRA; ETA; ETRA; Endothelin-1 receptor; Endothelin A receptor | |
| Target/Specificity This EDNRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132~162 amino acids from the Center region of human EDNRA. | |
| Dilution WB~~1:100~500WB~~1:1000 IF~~1:10~50 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions EDNRA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
EDNRA Antibody (Center) - Protein Information | |
| Name EDNRA | |
| Synonyms ETA, ETRA | |
| Function Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 | |
| Cellular Location Cell membrane; Multi-pass membrane protein. | |
| Tissue Location Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels | |
EDNRA Antibody (Center) - Related products
AP6507c: EDNRA Antibody (Center)
RI11678: EDNRA predesign siRNA
EDNRA Antibody (Center) - Application data
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Western blot analysis of EDNRA antibody (Center) (Cat.# AP6507c) in CEM cell line lysates (35ug/lane). EDNRA (arrow) was detected using the purified Pab.
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Confocal immunofluorescent analysis of EDNRA Antibody (Center)(Cat#AP6507c) with HepG2 cell followed by Alexa Fluor搴?488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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Flow cytometric analysis of CEM cells using EDNRA Antibody (Center) (green histogram) compared to a negative control cell (blue histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
EDNRA Antibody (Center) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
EDNRA is a receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
REFERENCES
Cardillo,C., Arthritis Rheum. 60 (6), 1840-1844 (2009) Hayzer,D.J., Am. J. Med. Sci. 304 (4), 231-238 (1992)
