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ARPC1A Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ARPC1A Antibody (Center) AP6519C
    Western blot analysis of ARPC1A antibody (Center) (Cat.# AP6519c) in Y79 cell line lysates (35ug/lane). ARPC1A (arrow) was detected using the purified Pab.
  • FC - ARPC1A Antibody (Center) AP6519C
    Flow cytometric analysis of hela cells using ARPC1A Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • IHC-P - ARPC1A Antibody (Center) AP6519C
    ARPC1A Antibody (Center) (Cat. #AP6519c) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ARPC1A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92747
Other Accession Q99PD4, Q9R0Q6, Q1JP79
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41569 Da
Antigen Region 157-184 aa
Additional Information
Gene ID 10552
Other Names Actin-related protein 2/3 complex subunit 1A, SOP2-like protein, ARPC1A, SOP2L
Target/Specificity This ARPC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-184 amino acids from the Central region of human ARPC1A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsARPC1A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SOP2L
Function Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Cellular Location Cytoplasm, cytoskeleton.
Research Areas
Citations (0)

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ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.


Laurila,E., Genes Chromosomes Cancer 48 (4), 330-339 (2009)
Machesky,L.M., Biochem. J. 328 (PT 1), 105-112 (1997)

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$ 295.00
$ 99.00
Cat# AP6519C
(40 western blots)
Availability: In Stock
Bulk Size
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