|Application ||WB, E|
|Calculated MW||12499 Da|
|Antigen Region||55-84 aa|
|Other Names||Mitochondrial import inner membrane translocase subunit TIM14, DnaJ homolog subfamily C member 19, DNAJC19, TIM14, TIMM14|
|Target/Specificity||This DNAJC19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the Central region of human DNAJC19.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DNAJC19 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).|
|Cellular Location||Mitochondrion inner membrane; Single-pass membrane protein|
|Tissue Location||Ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
DNAJC19 is a probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. The protein may act as a co-chaperone that stimulate the ATP-dependent activity.
Sparkes,R., Cardiol Young 17 (2), 215-217 (2007)
Davey,K.M., J. Med. Genet. 43 (5), 385-393 (2006)
Mokranjac,D., EMBO J. 22 (19), 4945-4956 (2003)
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