|Application ||WB, IHC-P, FC, E|
|Calculated MW||18099 Da|
|Antigen Region||32-61 aa|
|Other Names||Immunoglobulin J chain, IGJ, IGCJ|
|Target/Specificity||This IGJ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human IGJ.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IGJ Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.|
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Provided below are standard protocols that you may find useful for product applications.
IGJ serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Ramachandran,P., J. Proteome Res. 5 (6), 1493-1503 (2006)
Liu,T., J. Proteome Res. 4 (6), 2070-2080 (2005)
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