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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CTSF Antibody (Center D276)   

CTSF Antibody (Center D276)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CTSF Antibody (Center D276) AP6569b
    Western blot analysis of CTSF Antibody (Center D276) (Cat. #AP6569b) in MDA-MB231 cell line lysates (35ug/lane). CTSF (arrow) was detected using the purified Pab.
  • IHC-P - CTSF Antibody (Center D276) AP6569b
    CTSF Antibody (Center D276) (Cat. #AP6569b) IHC analysis in formalin fixed and paraffin embedded human Skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CTSF Antibody (Center D276) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - CTSF Antibody (Center D276) AP6569b
    CTSF Antibody (Center D276) (Cat. #AP6569b) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBX1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53366 Da
Antigen Region 261-290 aa
Additional Information
Gene ID 8722
Other Names Cathepsin F, CATSF, CTSF
Target/Specificity This CTSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-290 amino acids from the Central region of human CTSF.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTSF Antibody (Center D276) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Cellular Location Lysosome.
Tissue Location High expression levels in heart, skeletal muscle, brain, testis and ovary; moderate levels in prostate, placenta, liver and colon; and no detectable expression in peripheral leukocytes and thymus
Research Areas
Citations (0)

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Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF is a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway.


Kaakinen,R., Atherosclerosis 192 (2), 323-327 (2007)
Oorni,K., J. Biol. Chem. 279 (33), 34776-34784 (2004)

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$ 295.00
$ 99.00
Cat# AP6569b
(40 western blots)
Availability: In Stock
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