|Application ||WB, FC, E|
|Calculated MW||41251 Da|
|Antigen Region||164-195 aa|
|Other Names||Galactoside 2-alpha-L-fucosyltransferase 1, Alpha(1, 2)FT 1, Blood group H alpha 2-fucosyltransferase, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, FUT1, H, HSC|
|Target/Specificity||This FUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from the Central region of human FUT1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FUT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
FUT1 is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway.
Moehler,T.M., J. Cell. Physiol. 215 (1), 27-36 (2008)
Moore,G.T., Mol. Immunol. 45 (8), 2401-2410 (2008)
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