|Application ||WB, FC, E|
|Calculated MW||41251 Da|
|Antigen Region||164-195 aa|
|Other Names||Galactoside 2-alpha-L-fucosyltransferase 1, Alpha(1, 2)FT 1, Blood group H alpha 2-fucosyltransferase, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, FUT1, H, HSC|
|Target/Specificity||This FUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from the Central region of human FUT1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FUT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi|
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Provided below are standard protocols that you may find useful for product applications.
FUT1 is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway.
Moehler,T.M., J. Cell. Physiol. 215 (1), 27-36 (2008)
Moore,G.T., Mol. Immunol. 45 (8), 2401-2410 (2008)
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