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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Lamin B1 Antibody (C-term)   

Lamin B1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Lamin B1 Antibody (C-term) AP6586b
    Western blot analysis of Lamin B1 antibody (C-term) (Cat. #AP6586b) in Ramos cell line lysates (35ug/lane). Lamin B1 (arrow) was detected using the purified Pab.
  • IHC-P - Lamin B1 Antibody (C-term) AP6586b
    Lamin B1 Antibody (C-term) (Cat. #AP6586b) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Lamin B1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20700
Other Accession P70615, P14733
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 66408 Da
Antigen Region 459-488 aa
Additional Information
Gene ID 4001
Other Names Lamin-B1, LMNB1, LMN2, LMNB
Target/Specificity This Lamin B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-488 amino acids from the C-terminal region of human Lamin B1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLamin B1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LMNB1
Synonyms LMN2, LMNB
Function Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Cellular Location Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side
Research Areas
Citations (0)

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The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.


Martin,C., J. Cell. Sci. 122 (PT 10), 1551-1562 (2009)
Brussino,A., J. Neurol. Neurosurg. Psychiatr. 80 (2), 237-240 (2009)

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Cat# AP6586b
(40 western blots)
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