|Application ||WB, IHC-P, FC, E|
|Calculated MW||37651 Da|
|Antigen Region||270-297 aa|
|Other Names||Complement factor H-related protein 1, FHR-1, H factor-like protein 1, H-factor-like 1, H36, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2|
|Target/Specificity||This CFHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the C-terminal region of human CFHL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CFHL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1,|
|Function||Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
CFHL1 might be involved in complement regulation. The protein can associate with lipoproteins and may play a role in lipid metabolism.
Grosskinsky,S., PLoS ONE 4 (3), E4858 (2009)
Siegel,C., J. Biol. Chem. 283 (50), 34855-34863 (2008)
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