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TAGLN Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6678a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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TAGLN Antibody (N-term) - Product info | |
| Application | WB, IHC, FC
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| Primary Accession | Q01995 |
| Other Accession | P31232, P37804, Q9TS87 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 22611 Da |
TAGLN Antibody (N-term) - Additional info | |
| Gene ID 6876 | |
| Other Names TAGLN; SM22; WS3-10; Transgelin; 22 kDa actin-binding protein; Protein WS3-10; Smooth muscle protein 22-alpha | |
| Target/Specificity This TAGLN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30~60 amino acids from the N-terminal region of human TAGLN. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions TAGLN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
TAGLN Antibody (N-term) - Protein Information | |
| Name TAGLN | |
| Synonyms SM22, WS3-10 | |
| Function Actin cross-linking/gelling protein (By similarity). Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence | |
| Cellular Location Cytoplasm (Probable). | |
TAGLN Antibody (N-term) - Related products
AP6678a: TAGLN Antibody (N-term)
AP6678b: TAGLN Antibody (C-term)
RI15214: TAGLN predesign siRNA
DC01560: Human TAGLN cDNA Clone
LY11635a: TAGLN Over-expression Lysate
BP6678a: TAGLN Antibody (N-term) Blocking Peptide
BP6678b: TAGLN Antibody (C-term) Blocking Peptide
TAGLN Antibody (N-term) - Application data
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Western blot analysis of TAGLN antibody (N-term) (Cat. #AP6678a) in SK-Br-3 cell line lysates (35ug/lane). TAGLN (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human skeletal muscle reacted with TAGLN Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Flow cytometric analysis of MDA-MB468 cells using TAGLN Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
TAGLN Antibody (N-term) - Research Areas
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BACKGROUND
TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.
REFERENCES
Zhao,L., Mod. Pathol. 22 (6), 786-796 (2009) Leguillette,R., Am. J. Respir. Crit. Care Med. 179 (3), 194-204 (2009) Yu,H., FASEB J. 22 (6), 1778-1789 (2008)
