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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TTR Antibody (Center)   

TTR Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TTR Antibody (Center) AP6698C
    Western blot analysis of TTR Antibody (Center) (Cat. #AP6698c) in HepG2 cell line lysates (35ug/lane). TTR (arrow) was detected using the purified Pab.
  • IHC-P - TTR Antibody (Center) AP6698C
    Formalin-fixed and paraffin-embedded human hepatocarcinoma with TTR Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - TTR Antibody (Center) AP6698C
    TTR Antibody (Center) (Cat.#AP6698c) flow cytometry analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02766
Other Accession O46375
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 15887 Da
Antigen Region 47-74 aa
Additional Information
Gene ID 7276
Other Names Transthyretin, ATTR, Prealbumin, TBPA, TTR, PALB
Target/Specificity This TTR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-74 amino acids from the Central region of human TTR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTTR Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TTR
Synonyms PALB
Function Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Cellular Location Secreted. Cytoplasm.
Tissue Location Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver
Research Areas
Citations (0)

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Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.


Lee,K.W., Biochem. Biophys. Res. Commun. 388 (2), 256-260 (2009)

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Cat# AP6698C
(40 western blots)
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