|Application ||WB, E|
|Calculated MW||46325 Da|
|Antigen Region||37-65 aa|
|Other Names||Thyroxine-binding globulin, Serpin A7, T4-binding globulin, SERPINA7, TBG|
|Target/Specificity||This SERPINA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human SERPINA7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SERPINA7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Major thyroid hormone transport protein in serum.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
SERPINA7 is the major thyroid hormone transport protein in man (summarized by Mori et al., 1995 [PubMed 8530630]). Inherited abnormalities in the level of serum TBG have been classified as partial deficiency, complete deficiency, and excess. Patients are euthyroid.
Domingues, R., et al. Endocrine 36(1):83-86(2009)
Lacka, K., et al. Thyroid 17(11):1143-1146(2007)
Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Anderson, N.L., et al. Mol. Cell Proteomics 3(4):311-326(2004)
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