SERPINC1 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IF, FC, IHC-P, E |
---|---|
Primary Accession | P01008 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 52602 Da |
Antigen Region | 364-393 aa |
Gene ID | 462 |
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Other Names | Antithrombin-III, ATIII, Serpin C1, SERPINC1, AT3 |
Target/Specificity | This SERPINC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human SERPINC1. |
Dilution | WB~~1:1000 IF~~1:10~50 FC~~1:10~50 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SERPINC1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SERPINC1 |
---|---|
Synonyms | AT3 |
Function | Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade (PubMed:15140129, PubMed:15853774). AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa (PubMed:15140129). Its inhibitory activity is greatly enhanced in the presence of heparin. |
Cellular Location | Secreted, extracellular space. |
Tissue Location | Found in plasma. |

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