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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MVD Antibody (N-term)   

MVD Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MVD Antibody (N-term) AP6717a
    Western blot analysis of MVD (arrow) using rabbit polyclonal MVD Antibody (N-term) (Cat. #AP6717a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MVD gene (Lane 2).
  • IHC-P - MVD Antibody (N-term) AP6717a
    Formalin-fixed and paraffin-embedded human Skeletal muscle reacted with MVD Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P53602
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 43405 Da
Antigen Region 7-34 aa
Additional Information
Gene ID 4597
Other Names Diphosphomevalonate decarboxylase, Mevalonate (diphospho)decarboxylase, MDDase, Mevalonate pyrophosphate decarboxylase, MVD, MPD
Target/Specificity This MVD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human MVD.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMVD Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MVD
Synonyms MPD
Function Performs the first committed step in the biosynthesis of isoprenes.
Tissue Location Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta
Research Areas
Citations (0)

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The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.


Voynova,N.E., Arch. Biochem. Biophys. 480 (1), 58-67 (2008)
Hogenboom,S., Mol. Genet. Metab. 81 (3), 216-224 (2004)
Wadhwa,R., Biochem. Biophys. Res. Commun. 302 (4), 735-742 (2003)

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Cat# AP6717a
(40 western blots)
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