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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IGFBP6 Antibody (C-term)   

IGFBP6 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - IGFBP6 Antibody (C-term) AP6764b
    Western blot analysis of IGFBP6 Antibody (C-term) (Cat. #AP6764b) in CEM cell line lysates (35ug/lane). IGFBP6 (arrow) was detected using the purified Pab.
  • IHC-P - IGFBP6 Antibody (C-term) AP6764b
    Formalin-fixed and paraffin-embedded human colon carcinoma reacted with IGFBP6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - IGFBP6 Antibody (C-term) AP6764b
    Flow cytometric analysis of widr cells using IGFBP6 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, FC, E
Primary Accession P24592
Other Accession Q05718
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25322 Da
Antigen Region 176-200 aa
Additional Information
Gene ID 3489
Other Names Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6, IGFBP6, IBP6
Target/Specificity This IGFBP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-200 amino acids from the C-terminal region of human IGFBP6.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIGFBP6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGFBP6
Synonyms IBP6
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis.

References

Guey,L.T., et.al., Eur. Urol. (2009)

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$ 295.00
$ 99.00
Cat# AP6764b
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(40 western blots)
Availability: In Stock
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