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PFTK1 Antibody (N-term P82)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PFTK1 Antibody (N-term P82) AP6780a
    Western blot analysis of lysate from human brain tissue lysate, using PFTK1 Antibody (N-term P82)(Cat. #AP6780a). AP6780a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • IHC-P - PFTK1 Antibody (N-term P82) AP6780a
    PFTK1 Antibody (N-term P82) (RB18842) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PFTK1 Antibody (N-term P82) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - PFTK1 Antibody (N-term P82) AP6780a
    PFTK1 Antibody (N-term P82) (Cat. #AP6780a) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94921
Other Accession O35495
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53057 Da
Antigen Region 67-96 aa
Additional Information
Gene ID 5218
Other Names Cyclin-dependent kinase 14, Cell division protein kinase 14, Serine/threonine-protein kinase PFTAIRE-1, hPFTAIRE1, CDK14, KIAA0834, PFTK1
Target/Specificity This PFTK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human PFTK1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPFTK1 Antibody (N-term P82) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDK14
Synonyms KIAA0834, PFTK1
Function Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Cellular Location Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Note=Recruited to the cell membrane by CCNY
Tissue Location Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Also detected at lower levels in other tissues except in spleen and thymus where expression is barely detected.
Research Areas
Citations (0)

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PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family. It May play a role in meiosis as well as in neuron differentiation and/or function (By similarity).


Denoeud,F.,, Genome Res. 17 (6), 746-759 (2007)

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$ 295.00
$ 99.00
Cat# AP6780a
(40 western blots)
Availability: In Stock
Bulk Size
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