|Application ||WB, IHC-P, E|
|Other Accession||Q96QG7, NP_060147|
|Calculated MW||63462 Da|
|Antigen Region||518-549 aa|
|Other Names||Myotubularin-related protein 9, 313-, MTMR8|
|Target/Specificity||This MTMR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-549 amino acids from the C-terminal region of human MTMR8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MTMR9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable pseudophosphatase. Contains a Gly residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential).|
|Tissue Location||Expressed in many tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
MTMR8 is a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.
Appel, S., et al., Eur. J. Hum. Genet. 10(1):17-25 (2002).
Appel, S., et al., Genomics 75 (1-3), 6-8 (2001).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.