|Application ||WB, IHC-P, FC, E|
|Calculated MW||48218 Da|
|Antigen Region||285-313 aa|
|Other Names||Paired box protein Pax-8, PAX8|
|Target/Specificity||This PAX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-313 amino acids from the Central region of human PAX8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAX8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells.|
|Tissue Location||Expressed in the excretory system, thyroid gland and Wilms tumors|
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Provided below are standard protocols that you may find useful for product applications.
PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes.
Ramos,H.E., et.al., Thyroid 19 (1), 61-68 (2009)
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