|Application ||WB, IHC-P, FC, E|
|Calculated MW||91733 Da|
|Antigen Region||17-45 aa|
|Other Names||Espin, Autosomal recessive deafness type 36 protein, Ectoplasmic specialization protein, ESPN, DFNB36|
|Target/Specificity||This ESPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human ESPN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ESPN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection, stereocilium. Cell projection, microvillus|
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Provided below are standard protocols that you may find useful for product applications.
ESPN is a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells.
Boulouiz,R., et.al., Am. J. Med. Genet. A 146A (23), 3086-3089 (2008)
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