|Application ||WB, IHC-P, FC, E|
|Calculated MW||25982 Da|
|Antigen Region||24-51 aa|
|Other Names||Protein FAM3B, Cytokine-like protein 2-21, Pancreatic-derived factor, PANDER, FAM3B, C21orf11, C21orf76|
|Target/Specificity||This FAM3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human FAM3B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FAM3B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.|
|Cellular Location||Secreted. Note=Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure|
|Tissue Location||Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
FAM3B has delayed effects on beta-cell function, inhibiting basal insulin secretion from a beta-cell line in a dose-dependent manner.
Yang,J., et.al., Biochemistry 44 (34), 11342-11352 (2005)
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