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TMPRSS3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TMPRSS3 Antibody (Center) AP6936C
    Western blot analysis of TMPRSS3 Antibody (Center) (Cat. #AP6936c) in Hela, 293 cell line lysates (35ug/lane). TMPRSS3 (arrow) was detected using the purified Pab.
  • IF - TMPRSS3 Antibody (Center) AP6936C
    Confocal immunofluorescent analysis of TMPRSS3 Antibody (Center)(Cat#AP6936c) with hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P57727
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49405 Da
Antigen Region 272-300 aa
Additional Information
Gene ID 64699
Other Names Transmembrane protease serine 3, 3421-, Serine protease TADG-12, Tumor-associated differentially-expressed gene 12 protein, TMPRSS3, ECHOS1, TADG12
Target/Specificity This TMPRSS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the Central region of human TMPRSS3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMPRSS3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ECHOS1, TADG12
Function Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro).
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas
Research Areas
Citations (0)

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TMPRSS3 belongs to the serine protease family. This protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders.


Elbracht,M.,, J. Med. Genet. 44 (6), E81 (2007)

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Cat# AP6936C
(40 western blots)
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