|Application ||WB, IHC-P, FC, IF, E|
|Calculated MW||104786 Da|
|Antigen Region||30-58 aa|
|Other Names||Complement component C6, C6|
|Target/Specificity||This C6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human C6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||C6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.|
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Provided below are standard protocols that you may find useful for product applications.
C6 is a component of complement cascade. It is part of the membrane attack complex which can insert into the cell membrane and cause cell to lyse. People with C6 deficiency are prone to bacterial infection.
Wu,C., et.al., Proteomics 7 (11), 1775-1785 (2007)
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