|Application ||WB, IHC-P, FC, E|
|Calculated MW||58600 Da|
|Antigen Region||486-514 aa|
|Other Names||Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH, TH, TYH|
|Target/Specificity||This TH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 486-514 amino acids from the C-terminal region of human TH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in the physiology of adrenergic neurons.|
|Tissue Location||Mainly expressed in the brain and adrenal glands|
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Provided below are standard protocols that you may find useful for product applications.
TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons.
Kuhn,D.M., et.al., J. Biol. Chem. 277 (16), 14336-14342 (2002)
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