|Application ||WB, E|
|Calculated MW||63283 Da|
|Antigen Region||401-430 aa|
|Other Names||Serine/threonine-protein kinase RIO2, RIO kinase 2, RIOK2|
|Target/Specificity||This RIOK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human RIOK2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RIOK2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
RIOK2 belongs to the protein kinase superfamily; RIO-type Ser/Thr kinase family. Serine/threonine protein kinases, such as RIOK2, phosphorylate the OH group of serine or threonine (which have similar sidechains). Activity of these protein kinases can be regulated by specific events (e.g. DNA damage), as well as numerous chemical signals, including cAMP/cGMP, Diacylglycerol, and Ca2+/calmodulin.
Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).
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