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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PKLR Antibody (C-term)   

PKLR Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - PKLR Antibody (C-term) AP7043b
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
  • WB - PKLR Antibody (C-term) AP7043b
    The anti-PKLR Pab (Cat. #AP7043b) is used in Western blot to detect PKLR in mouse liver tissue lysate.
  • WB - PKLR Antibody (C-term) AP7043b
    PKLR Antibody (G536) (Cat. #AP7043b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PKLR antibody detected the PKLR protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30613
Other Accession P12928, P53657
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 61830 Da
Antigen Region 521-551 aa
Additional Information
Gene ID 5313
Other Names Pyruvate kinase PKLR, Pyruvate kinase 1, Pyruvate kinase isozymes L/R, R-type/L-type pyruvate kinase, Red cell/liver pyruvate kinase, PKLR, PK1, PKL
Target/Specificity This PKLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-551 amino acids from the C-terminal region of human PKLR.
Dilution IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPKLR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PK1, PKL
Function Plays a key role in glycolysis.
Research Areas
Citations (0)

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PKLR is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).


Wang, H., et al., Diabetes 51(9):2861-2865 (2002).
Valentini, G., et al., J. Biol. Chem. 277(26):23807-23814 (2002).
Mateu, E., et al., Hum. Genet. 110(6):532-544 (2002).
Indo, Y., et al., Hum. Mutat. 18(4):308-318 (2001).
Acan, N.L., et al., J. Enzym. Inhib. 16(5):457-464 (2001).

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$ 295.00
$ 99.00
Cat# AP7043b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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