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PRPS1/PRPS2/PRPS3 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRPS1/PRPS2/PRPS3 Antibody (N-term) AP7061A
    The anti-PRPS1/2/3 Pab (Cat. #AP7061a) is used in Western blot to detect PRPS1/2/3 in mouse kidney tissue lysate (Lane 1) and Hela cell lysate (Lane 2).
  • WB - PRPS1/PRPS2/PRPS3 Antibody (N-term) AP7061A
    Role of PPP during MSC transformation. (A) G6PD activity decreased during MSC transformation (∗, P=0.0132; t test). Western blot confirms the down-regulation of G6PD and the up-regulation of PRPS at the late stages of transformation.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P60891
Other Accession Q7ZXC9, P09330, Q9CS42, Q4R4R7, P11908, P60892, Q9D7G0, Q4R4U3, Q2HJ58
Reactivity Human, Mouse
Predicted Bovine, Monkey, Rat, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34834 Da
Antigen Region 79-109 aa
Additional Information
Gene ID 5631
Other Names Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1
Target/Specificity This PRPS1/PRPS2/PRPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of human PRPS1/PRPS2/PRPS3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRPS1/PRPS2/PRPS3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRPS1
Function Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
Research Areas
Citations ( 0 )


Phosphoribosylpyrophosphate synthetase (PRPS; EC catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine, pyrimidine, and pyridine biosynthesis. By PCR of human lymphoblast mRNA using primers based on the cDNA sequence of rat PRS I (Prps1), Roessler et al. (1990) isolated a partial human PRPS1 cDNA. They used this partial cDNA to screen lymphoblast cDNA libraries and isolated additional cDNAs corresponding to the entire PRPS1 coding region. The deduced PRPS1 protein has 318 amino acids.


Roessler, B. J., et al. Nucleic Acids Res. 18: 193 (1990).

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$ 295.00
$ 99.00
Cat# AP7061A
(40 western blots)
Availability: In Stock
Bulk Size
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