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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   STK38 Antibody (C-term)   

STK38 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - STK38 Antibody (C-term) AP7074b
    The anti-STK38 Pab (Cat. #AP7074b) is used in Western blot to detect STK38 in SK-Br-3 (left) and Jurkat (right) cell line lysates.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15208
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54190 Da
Antigen Region 410-439 aa
Additional Information
Gene ID 11329
Other Names Serine/threonine-protein kinase 38, NDR1 protein kinase, Nuclear Dbf2-related kinase 1, STK38 {ECO:0000312|EMBL:AAH120851}
Target/Specificity This STK38 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human STK38.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTK38 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STK38 {ECO:0000312|EMBL:AAH12085.1}
Function Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2.
Cellular Location Nucleus. Cytoplasm.
Tissue Location Ubiquitously expressed with highest levels observed in peripheral blood leukocytes
Research Areas
Citations (0)

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Stk38,also known as NUCLEAR DBF2-RELATED PROTEIN, contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.


Devroe, E., et al., J. Biol. Chem. 279(23):24444-24451 (2004).
Tamaskovic, R., et al., J. Biol. Chem. 278(9):6710-6718 (2003).
Tripodis, N., et al., Genome Res. 8(6):631-643 (1998).
Millward, T., et al., Proc. Natl. Acad. Sci. U.S.A. 92(11):5022-5026 (1995).

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$ 295.00
$ 99.00
Cat# AP7074b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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