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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ADK Antibody (C-term)   

ADK Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ADK Antibody (C-term) AP7091b
    Western blot analysis of anti-ADK Pab (Cat. #AP7091b) in mouse liver tissue lysate (35ug/lane). ADK(arrow) was detected using the purified Pab.
  • IHC-P - ADK Antibody (C-term) AP7091b
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ADK antibody (C-term) (Cat.#AP7091b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55263
Other Accession NP_006712
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40545 Da
Antigen Region 322-352 aa
Additional Information
Gene ID 132
Other Names Adenosine kinase, AK, Adenosine 5'-phosphotransferase, ADK
Target/Specificity This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsADK Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADK
Function ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Cellular Location Isoform 1: Nucleus.
Tissue Location Widely expressed. Highest level in placenta, liver, muscle and kidney
Research Areas
Citations ( 0 )


Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.


Szkotak, A.J., et al., J. Membr. Biol. 192(3):169-179 (2003). Singh, B., et al., DNA Cell Biol. 20(1):53-65 (2001). Van Rompay, A.R., et al., Eur. J. Biochem. 261(2):509-517 (1999). Mathews, I.I., et al., Biochemistry 37(45):15607-15620 (1998). McNally, T., et al., Biochem. Biophys. Res. Commun. 231(3):645-650 (1997).

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$ 295.00
$ 99.00
Cat# AP7091b
(40 western blots)
Availability: In Stock
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