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PANK1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PANK1 Antibody (Center) AP7159b
    Western blot analysis of anti-PANK1 Pab (Cat. #AP7159b) in mouse kidney tissue lysate (35ug/lane). PANK1(arrow) was detected using the purified Pab.
  • IHC-P - PANK1 Antibody (Center) AP7159b
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TE04
Other Accession Q8K4K6
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 64339 Da
Antigen Region 332-360 aa
Additional Information
Gene ID 53354
Other Names Pantothenate kinase 1, hPanK, hPanK1, Pantothenic acid kinase 1, PANK1, PANK
Target/Specificity This PANK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-360 amino acids from the Central region of human PANK1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPANK1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PANK1
Synonyms PANK
Function Plays a role in the physiological regulation of the intracellular CoA concentration.
Cellular Location Cytoplasm.
Tissue Location Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle
Research Areas
Citations (0)

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PANK1 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA.


Ramaswamy, G., et al., J. Lipid Res. 45(1):17-31 (2004).
Ni, X., et al., Int. J. Biochem. Cell Biol. 34(2):109-115 (2002).
Zhou, B., et al., Nat. Genet. 28(4):345-349 (2001).
Westaway, S.K., et al., Int. J. Biochem. Cell Biol. 34 (12), 1629 (2002) (): ().
Robishaw, J.D., et al., Am. J. Physiol. 248 (1 PT 1), E1-E9 (1985) (): ().

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$ 295.00
$ 99.00
Cat# AP7159b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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