|Application ||WB, IHC-P, E|
|Calculated MW||61141 Da|
|Antigen Region||60-90 aa|
|Other Names||Uridine-cytidine kinase-like 1, UCKL1, URKL1|
|Target/Specificity||This URKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the N-terminal region of human URKL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||URKL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May contribute to UTP accumulation needed for blast transformation and proliferation.|
|Cellular Location||Cytoplasm. Nucleus. Note=EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location|
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Provided below are standard protocols that you may find useful for product applications.
Uridine kinase is a key enzyme in the pyrimidine salvage pathway of all mammalian cells. URKL1 (uridine kinase-like 1) is highly similar in structure and sequence to uridine kinase.
Kashuba, E., et al., (er) BMC Cell Biol. 3 (1), 23 (2002) (): ().
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