|Application ||WB, IHC-P, E|
|Calculated MW||58051 Da|
|Antigen Region||374-404 aa|
|Other Names||Serine/threonine-protein kinase 35, CLP-36-interacting kinase 1, CLIK-1, PDLIM1-interacting kinase 1, Serine/threonine-protein kinase 35 L1, STK35, CLIK1, PDIK1, STK35L1|
|Target/Specificity||This STK35 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-404 amino acids from the Central region of human STK35.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STK35 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CLIK1, PDIK1, STK35L1|
|Cellular Location||Nucleus. Nucleus, nucleolus. Cytoplasm. Note=When associated with PDLIM1, it is mostly found in cytoplasm, localized to actin stress fibers (PubMed:11973348). However, PubMed:19756140 detected STK35 only in the nucleus, and the presence of PDLIM1 had no influence on its location|
|Tissue Location||Expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
STK35 can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded kinase may be a regulator of actin stress fibers in nonmuscle cells. This protein has also been found in the nucleus.
Vallenius, T., et al., J. Cell. Sci. 115 (Pt 10), 2067-2073 (2002).
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