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NFE2L2 Antibody (S40)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NFE2L2 Antibody (S40) AP7275D
    Western blot analysis of NFE2L2-S40 (Cat.#AP7275d) in T47D(lane 1) and 293(lane 2) cell line lysates (35ug/lane). NFE2L2 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16236
Other Accession NP_006155
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 67827 Da
Antigen Region 12-44 aa
Additional Information
Gene ID 4780
Other Names Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2, NFE2L2, NRF2
Target/Specificity This NFE2L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-44 amino acids from human NFE2L2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNFE2L2 Antibody (S40) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NFE2L2
Synonyms NRF2
Function Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Cellular Location Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents
Tissue Location Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle
Research Areas
Citations (0)

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NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).


Zhao,X., Stroke 38 (12), 3280-3286 (2007)
Li,M.H., J. Biol. Chem. 282 (39), 28577-28586 (2007)

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Cat# AP7275D
(40 western blots)
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