ECGF1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | P19971 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 49955 Da |
Antigen Region | 318-345 aa |
Gene ID | 1890 |
---|---|
Other Names | Thymidine phosphorylase, TP, Gliostatin, Platelet-derived endothelial cell growth factor, PD-ECGF, TdRPase, TYMP, ECGF1 |
Target/Specificity | This ECGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-345 amino acids from the Central region of human ECGF1. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ECGF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TYMP (HGNC:3148) |
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Synonyms | ECGF1 |
Function | May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ECGF1 is an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in the gene encoding ECGF1 have been associated with mitochondrial neurogastrointestinal encephalomyopathy.
References
Stenman,G.,Cytogenet. Cell Genet. 59 (1), 22-23 (1992)
Jinfeng,M.,Hepatogastroenterology 54 (78), 1635-1640 (2007)
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