|Application ||WB, E|
|Calculated MW||79097 Da|
|Antigen Region||49-78 aa|
|Other Names||Calpain-9, 3422-, Digestive tract-specific calpain, New calpain 4, nCL-4, Protein CG36, CAPN9, NCL4|
|Target/Specificity||This CAPN9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of human CAPN9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CAPN9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-regulated non-lysosomal thiol-protease.|
|Tissue Location||Expressed predominantly in stomach.|
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Provided below are standard protocols that you may find useful for product applications.
CAPN9 has been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This protein is thought to be associated with gastric cancer.
Huang,Y. and Wang,K.K. Trends Mol Med 7 (8), 355-362 (2001)
Lee,H.J., Tomioka,S. Arch. Biochem. Biophys. 362 (1), 22-31 (1999)
Lee,H.J., Sorimachi,H. Biol. Chem. 379 (2), 175-183 (1998)
Suzuki,K., Sorimachi,H. Biol. Chem. Hoppe-Seyler 376 (9), 523-529 (1995)
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