KRT9 Antibody (Center K444)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P35527 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 62064 Da |
Antigen Region | 429-456 aa |
Gene ID | 3857 |
---|---|
Other Names | Keratin, type I cytoskeletal 9, Cytokeratin-9, CK-9, Keratin-9, K9, KRT9 |
Target/Specificity | This KRT9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 429-456 amino acids from the Central region of human KRT9. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KRT9 Antibody (Center K444) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KRT9 |
---|---|
Function | May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly. |
Tissue Location | Expressed in the terminally differentiated epidermis of palms and soles. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KRT9 is the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this protein cause epidermolytic palmoplantar keratoderma.
References
Feng,W., Han,W. Eur J Dermatol 18 (4), 387-390 (2008)
Zhao,J.J., Zhang,Z.H. Int. J. Dermatol. 47 (6), 634-637 (2008)
Torchard,D., Blanchet-Bardon,C. Nat. Genet. 6 (1), 106-110 (1994)
Reis,A., Kuster,W. Hum. Genet. 90 (1-2), 113-116 (1992)
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