|Application ||WB, IHC-P, FC, E|
|Calculated MW||62064 Da|
|Antigen Region||302-331 aa|
|Other Names||Keratin, type I cytoskeletal 9, Cytokeratin-9, CK-9, Keratin-9, K9, KRT9|
|Target/Specificity||This KRT9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 amino acids from the Central region of human KRT9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Precautions||KRT9 Antibody (Center K317) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.|
|Tissue Location||Expressed in the terminally differentiated epidermis of palms and soles.|
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Provided below are standard protocols that you may find useful for product applications.
KRT9 is the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this protein cause epidermolytic palmoplantar keratoderma.
Feng,W., Han,W. Eur J Dermatol 18 (4), 387-390 (2008)
Zhao,J.J., Zhang,Z.H. Int. J. Dermatol. 47 (6), 634-637 (2008)
Torchard,D., Blanchet-Bardon,C. Nat. Genet. 6 (1), 106-110 (1994)
Reis,A., Kuster,W. Hum. Genet. 90 (1-2), 113-116 (1992)
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